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引物探针合成服务


产品介绍

修饰标记引物探针作为新一代分子生物学研究工具，已成为分子诊断、临床检验以及基础生物医学研究的主流技术平台，广泛应用于传染病、肿瘤、遗传病、个体化用药的分子诊断。


艾博思生物可以提供多种类型的修饰/标记引物，包括：Taqman探针、MGB taqman探针、双淬灭探针、STR单标荧光PCR引物、光谱矫正matrix标准品(STR探针)、恒温扩增PCR探针、分子信标（barcode）、FISH引物及数字PCR引物等类型，并为修饰标记引物建立起完全匹配应用的一套质量标准体系及检测方式。

产品内容

单标与普通修饰

分 类修饰标记纯化方式报价(元)备注
2 OD4 OD5 OD10 OD
稀有碱基DiPAGE607278120单碱基
dUPAGE90108117180单碱基
m5CPAGE200200200350单碱基
m6APAGE500500500700单碱基
2'-O-Methyl 碱基PAGE300300300500单碱基
2F-RNA 碱基PAGE300300300500单碱基
RNA 碱基PAGE300300300500单碱基
3’-纤维素 dTPAGE400400400750单碱基
DC-BrPAGE400400400750单碱基
LNA-XPAGE400400400750单碱基
5-Methyl dCPAGE60606080单碱基
硫代修饰(Phosphorothioates)SPAGE44.85.28单位点
磷酸基团 (Phosphorylation)5' PHOPAGE100120130200
3' PHOPAGE120144156240
NH2修饰(Amino Linkers)5' NH2 C6HPLC180216234360
3' NH2 C7HPLC180216234360
5' NH2 C12HPLC5206246761040
SH修饰(Thiol)3' SH C3HPLC320384416640
5' SH C6HPLC320384416640
生物素(Biotin)5' BiotinHPLC160192208320
3' Biotin TEGHPLC240288312480
地高辛(Digoxigenin)5' DIGHPLC5806967541160
3' DIGHPLC6007207801200
荧光基团(Fluorescence)5' Cy3HPLC6407688321280
3' Cy3HPLC6407688321280
3' Cy3HPLC6407688321280
3' Cy5HPLC6407688321280
5' FAMHPLC200240260400
3' FAMHPLC200240260400
5' HEXHPLC320384416640
5' TETHPLC320384416640
5' -FITCHPLC240288312480
3'-FITCHPLC240288312480
5' 6-JOEHPLC5206246761040
3' 6-JOEHPLC5506607151100
5' ROXHPLC5206246761040
3' ROXHPLC5506607151100
5' TAMRAHPLC400480520800
3' TAMRAHPLC5006006501000
3’-HEXHPLC5006006501000
3’-TETHPLC5006006501000
5'Helix Flour555HPLC5006006501000
3'Helix Flour555HPLC5006006501000
5'Helix Flour575HPLC5006006501000
3'Helix Flour575HPLC5006006501000
5'Texas RedHPLC5006006501000
3'Texas RedHPLC5006006501000
5'Quasar 570HPLC5006006501000
3'Quasar 570HPLC5006006501000
5'Quasar 670HPLC5006006501000
3'Quasar 670HPLC5006006501000
5' Cy3.5HPLC5006006501000
3' Cy3.5HPLC5006006501000
5'Cy5.5NSHPLC5006006501000
3'Cy5.5NSHPLC5006006501000
5' Cy7NSHPLC5006006501000
3' Cy7NSHPLC5006006501000
5'&3' CAL Fluor Red 590HPLC5006006501000
5'&3'CAL Fluor Red 610HPLC5006006501000
5'&3'DABCYLHPLC5006006501000
5'&3'AMCAHPLC5006006501000
5'&3'DEACHPLC5006006501000
5'&3'MCAHPLC5006006501000
5'&3'LRB RedHPLC5006006501000
5'&3'CR6GHPLC5006006501000
5'&3' Bodi Fluor R6GHPLC5006006501000
5'&3'NBD-XHPLC5006006501000
5'&3'California RedHPLC5006006501000
5'&3'iFlour系列HPLC5006006501000
5'-VICHPLC5006006501000
3'-LC RED-610HPLC5006006501000
3'-LC RED-640HPLC5006006501000
3'-LC RED-705HPLC5006006501000
3'-Bodipy 493/503HPLC5006006501000
3'-Bodipy 564/570HPLC5006006501000
3'-Bodipy 581/591HPLC5006006501000
3'-Bodipy 630/650HPLC5006006501000
3'-Bodipy 650/665HPLC5006006501000
3'-BODIPY R6GHPLC5006006501000
5'-SIMAHPLC5006006501000
5'-NEDHPLC80096010401600
淬灭基团(Quenchers)3' DABCYLHPLC400480520800
3’TAMRAHPLC400480520800
3' BHQ 1HPLC360432468720
3' BHQ 2HPLC5506607151100
3' BHQ3HPLC400480520800
3'-MGBHPLC6507808451300
3’BBQ-650HPLC400480520800
3’TQ1-TQ6系列HPLC400480520800
3’-QSY 7 carboxylic acidHPLC6507808451300
3’TQ7HPLC400480520800
3’eclipseHPLC400480520800
其他修饰Spacer9(空间子)HPLC300300300500
Azide(叠氮化)HPLC300300300500
DBCOHPLC300300300500
Spacer(C6)HPLC400400400750
Spacer(C12)HPLC400400400750
Spacer C3HPLC300300300500
Spacer C18HPLC300300300500
dSpacerHPLC300300300500
5'&3,-CHOLHPLC400480520800
5',-CHCHHPLC6407688321280
3',-CHCHHPLC400480520800
5'-AcryditeHPLC400480520800
Inverted BaseHPLC300300300500
5’-Carboxy C10(羧基)HPLC400400400750
5’-D4PAHPLC400400400750
5’-AcridineHPLC400400400750
3'ddCHPLC300300300500
Alexa Flour 647HPLC300300300500
Yakima Yellow EpochHPLC300300300500
PyreneHPLC300300300500
中间修饰Int NH2 dTHPLC6006006001000
Int Biotin dTHPLC8008008001000
Int Cy3 dTHPLC8008008001000
Int Cy5 dTHPLC8008008001000
Int TAMRA dTHPLC8008008001000
Int ROX dTHPLC8008008001000
Int FAM dTHPLC8008008001000
Int HEX dTHPLC8008008001000
Int Dig dTHPLC8008008001000
Int CHCH dTHPLC8008008001000
Int DBCO dTHPLC8008008001000
Int Azide dTHPLC8008008001000
Int TAMRA dTHPLC8008008001000
Int ATTO Flour dTHPLC8008008001000
Int BHQ1 dTHPLC8008008001000
Int BHQ2 dTHPLC8008008001000
Int HS-SH C6HPLC8008008001000
Int Alexa Flour dTHPLC8008008001000
Int AzobenzeneHPLC8008008001000
Int Ferrocene dTHPLC8008008001000
dT- LC RED-610HPLC8008008001000
dT- LC RED-640HPLC8008008001000
dT- LC RED-705HPLC8008008001000
dC-FluoresceinHPLC8008008001000
dC-TamraHPLC8008008001000
dC-AminoHPLC8008008001000
dC-RoxHPLC8008008001000
dC-DigoxinHPLC8008008001000
dC-FITCHPLC8008008001000
dC-Texas RedHPLC8008008001000
备注：
1、艾博思可以进行大规模合成，合成规格可以从10 OD～5000 OD，欢迎询价（order@ibsbio.com）。
2、公司在工业级水解探针、STR探针、捕获探针等方面拥有专业的设备及生产工艺，欢迎询价（order@ibsbio.com）。

引物及纯化费用报价

项 目要 求价 格备注
修饰中普通碱基＜60 bp1元/bp
≥60 bp2元/bp
HPLC纯化费用2～10 OD50元/条

双标修饰

分 类修饰标记纯化方式报价(元)备 注
2 OD4 OD5 OD10 OD
TAMRA5' FAM-3' TAMRAHPLC900108011701800
5' HEX-3' TAMRAHPLC1100132014302200
5' TET-3' TAMRAHPLC1100132014302200
5' JOE-3' TAMRAHPLC1200144015602400
5＇VIC-3＇TAMRAHPLC1200144015602400
BHQ15' FAM-3' BHQ1HPLC80096010401600
5' VIC-3' BHQ1HPLC1100132014302200
5' HEX-3' BHQ1HPLC960115212481920
5' JOE-3' BHQ1HPLC960115212481920
5' TET-3' BHQ-1HPLC960115212481920
BHQ25' Cy5-3' BHQ2HPLC960115212481920
5' Cy3-3' BHQ2HPLC960115212481920
5' ROX-3' BHQ2HPLC960115212481920
5' TET-3' BHQ2HPLC960115212481920
5'JOE-3'BHQ2HPLC960115212481920
5'HEX-3'BHQ2HPLC960115212481920
5'TAMRA-3'BHQ2HPLC960115212481920
5'Texas Red-3'BHQ2HPLC960115212481920
5'Quasar 670-3'BHQ2HPLC960115212481920
5'-FAM and 3'-BHQ2HPLC960115212481920
BHQ35'Quasar 670-3'BHQ3HPLC960115212481920
5'CY5-3'BHQ3HPLC960115212481920
ECLIPS5' FAM-3' ECLIPSHPLC960115212481920
5' HEX-3' ECLIPSHPLC960115212481920
5'TAMRA-3'EclipseHPLC960115212481920
5'ROX-3'EclipseHPLC960115212481920
5＇TET-3＇EclipseHPLC960115212481920
5' JOE-3' EclipseHPLC960115212481920
MGB5' FAM-3'MGBHPLC1200144015602400
5' HEX-3'MGBHPLC1200144015602400
5'TET-3'MGBHPLC1200144015602400
5'JOE-3'MGBHPLC1200144015602400
5'ROX-3'MGBHPLC1200144015602400
5'Texas Red-3'MGBHPLC1200144015602400
5'Quasar 670-3'MGBHPLC1200144015602400
5' VIC-3'MGBHPLC2000240026004000
Dabcyl5' FAM-3' DABCYLHPLC960115212481920
5' HEX-3' DABCYLHPLC960115212481920
5' TET-3' DABCYLHPLC960115212481920
5' JOE-3' DABCYLHPLC960115212481920
5' TAMRA-3' DABCYLHPLC960115212481920
5'Texas Red-3'DabcylHPLC960115212481920
5'ROX-3'DabcylHPLC960115212481920
5'CY3-3'DABCYLHPLC960115212481920
5' Cy5-3' DABCYLHPLC960115212481920
其他双标5’Phos and 3’FAMHPLC400400400500
5’TAMRA and 3’PhosHPLC400400400500
5＇C6-Biotin,3＇BiotinHPLC400400400500
5＇C6-Biotin,3＇Cy5HPLC500500500700
5＇C6-NH2,3＇C3-FamHPLC400400400500
5＇C6-NH2,3＇Cy3HPLC700700700900
5＇Cy5,SS,HPLC700700700900
5＇Cy5,3＇C7-NH2HPLC700700700900
5＇Cy5,3＇SHHPLC700700700900
5＇Dabcyl,3＇C3-FamHPLC700700700900
5＇DlG,3＇DigoxinHPLC700700700900
5＇SH,3＇Cy3HPLC700700700900
5＇Fam,3＇C3-FamHPLC400400400500
5＇TAMRA，3＇C3-FamHPLC500500500700


备注：

1、公司可以进行大规模合成，合成规格可以从10 OD～5000 OD，欢迎咨询。
2、公司在工业级水解探针、STR探针(专利)、荧光定量PCR引物、DNA编码化合物建库引物、Taqman探针、捕获探针、水解探针、FISH探针、NGS引物、大OD普通引物、RNA合成等工业级别引物方面拥有专业的设备及生产工艺，欢迎询价。

引物及纯化费用报价

项 目要 求价 格备注
修饰中普通碱基＜60 bp1元/bp
≥60 bp2元/bp
HPLC纯化费用2～10 OD50元/条



服务优势

  • 低突变率：低于1/1000

  • 专业及时的技术反馈：技术支持反馈时间保证1小时以内

  • 高度定制化： 提供0.5～10 OD的规格(对一次性合成大量的引物可以96孔板或384孔板的形式进行发货)

  • 稳定性高：采用独特的冻干工艺，减少荧光素在加热干燥过程中损伤；冻干粉末为弱碱性，避免降解导致荧光基团脱落

  • 纯化方式多样：脱盐到HPLC等四种纯化方式可选

  • 质量控制：完善的中控，实时监测每个碱基的偶联效率，确保每步效率大于99%；成品检测采用ESI-MS、CE、UPLC、全波长扫描、荧光光谱检测、PAGE分析胶检测等6重QC